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What is Sustained Release?

December 29, 2023

What is Sustained Release?cid=15


Sustained release is a type of dosage form which is designed to release the active ingredients at a predetermined rate in order to maintain a constant concentration for a specific period of time with minimum side effects.


It denotes a dietary supplement preparation in a capsule containing numerous tiny pellets with different coatings that release their ingredients steadily over a long period, e.g., 8 hours. Or we can design the release rate as your requirements.


With advanced coating technology as well as other production technology, we can design and control the release time as per customers' requirements. Single or multiple active ingredients both can be produced into sustained release products.


What is Sustained Release?cid=15


Advantages of Sustained Release Dosage Form

1.It can reduce the frequency of taking supplements and enhance compliance.  Ordinary supplements generally need to be taken several times a day, but sustained release supplements generally only need to be taken once a day.


2. Blood concentration level of ingredients after taking SR products is reduced. So Side effects such as irritation to the stomach will be reduced.

Common supplements are not uniformly released, and there will be a state of high blood concentration and low blood concentration, which is called "peak-valley phenomenon". When the blood concentration is too high, it is easy to cause side effects, when the blood concentration is too low, the ideal effect cannot be achieved.


3. It can improve the effect of active ingredients and better control of dietary supplement absorption.

The slow release supplements can greatly reduce the fluctuation of blood concentration of active ingredients, so that the human body can obtain a stable and effective supply of nutrients in blood.


4. It can reduce the ingredient's irritation to the gastrointestinal tract. Ordinary preparations disintegrate and dissolve quickly in the gastrointestinal tract after taken orally, and cause greater irritation to the gastrointestinal tract. If a sustained-release preparation is made, it can reduce the negative effect caused by the rapid dissolution of the active ingredients.


5. More economic and convenient,maximizing availability with minimum dose, improve the efficiency of health food in promoting health.

It can reduce the total dose of the supplement, a smaller dose can be used to achieve a better effect.  As far as the dosage of a single tablet (capsule) is concerned, although the dose of sustained release formulations is higher than that of ordinary formulations, the total amount of supplements used is reduced due to the reduction in the frequency of taking supplements.


What is Sustained Release?cid=15


Introduction of our pellets

Using the latest coating technology and advanced equipment, our company can produce and supply tailor-made Sustained/Slow-release pellet products to our customers.


Our SR pellets are small, perfectly round beadlets of active ingredients that come in any size and color. Our SR pellets are 100% natural, gluten free, free of allergens, free of artificial colorants.


Our company can provide you pellets as raw material in bulk or ready to go in a capsule, with a minimum order quantity of 50kg according your dosage, the size and the color.


Release profile

Recent scientific insights show that precision released nutritional supplements accurately deliver active ingredients to the part of the body where they have to be absorbed,the stomach or the colon, for example.


We formulate the pellet with our technology and test the dissolution profile in gastric acid juice, with a temperature of 37 degrees centigrade and a pH of 6.8.


After successfully completing the dissolution profile test, the product will be produced accordingly and supplied to the clients.


Application

What is Sustained Release?cid=15

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